We’re looking for a Principal Computational Scientist/Director to help translate our foundation models into impactful, real-world discovery workflows. In this role, you’ll provide scientific leadership across model evaluation and applied use cases, ensuring our work stays grounded in the most relevant challenges in drug development and translational research.
You’ll join as a senior individual contributor with leadership and strategy experience at a point where the the team scales. You will act as a key scientific partner to our research team, mentor and support junior colleagues, and work closely with Product and Business Development to turn cutting-edge biology + ML into deliverables that matter for customers.
Requirements
- PhD in Computational Biology, Machine Learning, Bioinformatics, or a related field, with a strong focus on Transcriptomics OR Genomics + ML , and 2+ years of industry (non-academic) experience OR MSc in a relevant field and 5+ years of industry experience applying ML to Transcriptomics OR Genomics problems
- Strong understanding of ML/AI methods for biological data (e.g., transformers, VAEs, diffusion models, classical ML )
- Hands-on experience with modern ML frameworks such as PyTorch (or equivalent)
- Leadership experience with small teams to work towards defined roadmaps or projects
- Excellent communication skills — able to translate complex science into clear, actionable insights for technical and non-technical stakeholders
- Comfortable in a fast-paced, high-iteration environment , moving quickly from prototype → experiment → insight
- Strong passion for building at the intersection of biology and machine learning
Vacancy posted more than 2 months ago
Similar jobs that could be interesting for youBased on the Principal Scientist (Comp. Bio/ML) - Director Level in London vacancy
- £77k - £102k per annumEstimated...Viator, and TheFork. About the role: As a Principal Machine Learning Scientist , you will be the technical anchor for our core... ...systems within the Trips vertical. Translate high-level business goals into concrete ML architectures and scalable production systems....PrincipalLong-term contractFull-timeHybrid workingRemoteFlexible hours
- £50k - £66k per annumEstimated...curiosity and high standards, you will leave a mark that lasts well beyond any individual survey or report. We are looking for a Senior Principal Ecologist to join a growing team that is ambitious, collaborative and deeply committed to doing ecology well. If you are ready to...PrincipalPermanentFull-timeHybrid workingFlexible hours
- £128k - £167k per annumEstimated...Here at Cleo, we have ~70 Data Scientists (Product Analysts) working... ...senior ICs - setting company-level standards for metrics, experimentation... ...Engineering, Commercial, and ML leadership to shape roadmaps... ...hold your own with Product Directors and Commercial stakeholders...Suggested
- £36k - £47k per annumEstimated.... We are looking for an exceptional Principal Applied Scientist to define and drive the science vision... ...Strong publication record in top-tier ML/AI conferences (NeurIPS, ICML, KDD, ACL... ...processing terabytes of data Expert-level proficiency in Python and at least one...PrincipalShift work
- £70k - £90k per annumEstimatedWealth & Asset Management Discretionary / Advisory Specialist Location: London (Hybrid) | Practice Area: Wealth & Asset Management | Type: Permanent Shape the future of Wealth & Asset Management The Role Capco is a key consulting partner to leading ...PrincipalPermanentHybrid working
£123k - £129k per annum
...impact on the performance of the Waymo Driver. You have: ~ PhD in ML or related in AI/CS, or MSc with a strong academic publication... ...location, experience, relevant training and education, and skill level. Waymo employees are also eligible to participate in Waymo’s discretionary...Full-timeHybrid working- £63k - £82k per annumEstimated...satisfaction. The Senior Machine Learning Scientist sits on the Lodging Search Ranking AI team... ...~ Safely integrate and operate AI/ML-enabled solutions that improve outcomes, including... ...solutions at the service or multi-service level, including problem definition, model...
£22k per annum
...Requirements: Have or are predicted 5 GCSEs including English Language and Maths at grade 4 or above. Have or are predicted a minimum of one A-level or equivalent. Locations Available: Hybrid working with a minimum of 3 days required weekly at our Kingston or London Blackfriars...ApprenticeshipHybrid workingFree visaOn-siteImmediate startWork visaFlexible hours- £79k - £101k per annumEstimated...Join the ranks of top talent at one of the world’s most influential companies. As a Principal Software Engineer at JPMorganChase within the Chief Data & Analytics Office (CDAO) AI/ML Data Platforms Team, you provide deep engineering expertise and work across agile teams...PrincipalLong-term contractOn-site
- £50k - £66k per annumEstimated...passionate about bettering business and the world through AI. Ready to level up your career at the company leading workforce transformation in... ...? Fin's Machine Learning team is responsible for defining new ML features, researching appropriate algorithms and technologies, and...Hybrid workingOn-siteWork from home
- £53k - £72k per annumEstimated...TheFork. As our new Senior Machine Learning Scientist you’ll be joining the Tripadvisor... ...: Act as the technical lead for specific ML projects within your pod. Design and implement... ...feature distribution shifts). Lead team-level post-mortems and resolve blocking...Hybrid workingRemoteFlexible hoursShift work
- £45k - £57k per annumEstimatedPrincipal Physicist London, The Harley Street Clinic Full time, 37.5 hours per week... ...their area of work and contributes at a high level to departmental and service line... ...bring: HCPC registration as a clinical scientist in the field of radiotherapy physics MPE...PrincipalPermanentFull-timeLive-inMonday to FridayFlexible hoursShift work
- £41k - £54k per annumEstimated...from you! We’re looking to appoint a Principal Hydrologist to join our Water Civil Engineering... ...the wider team and Associates/Associate Directors. You'll take ownership and lead on... ...supporting your ambitions and interests at every level. We will provide you with an inspiring...PrincipalHybrid working
- £59k - £77k per annumEstimated...2027 Interviews: Thursday, 22 October at 9am As Assistant Principal, you will have high expectations and be focused on delivering excellent... ...environments Qualification Criteria Qualified to degree level and above Right to work in the U.K. Hold QTS (qualified...PrincipalPermanentFull-time
- £48k - £63k per annumEstimated...continued growth, SLR has an exciting opportunity for an experienced Hydrologist to join our growing London team at Associate or Principal level . This role is ideal for someone looking to broaden their responsibilities beyond technical delivery and take a more active...PrincipalFull-timePart-timeHybrid workingFlexible hours
- £55k - £70k per annumEstimated...direction. ~ Collaborate with engineers, product managers, applied scientists, and domain experts to translate ambiguous business problems into scalable ML solutions. ~ Contribute to system design, low-level design, API development, and data modelling for production...
- £61k - £81k per annumEstimated...Job Purpose As a senior leader, a Principal Consultant in the HEOR modelling team has responsibility... ...on complex projects Acting as Project Director on key engagements, assuring quality,... ...communication across all organisational levels Results-oriented with a strong...Principal
- £56k - £73k per annumEstimated...Assessment and Biodiversity Net Gain assessments. Ideally strong botanical skills, including Field Identification Skills Certificate (FISC) level 3+, or demonstrable botanical ability matching this level. Exceptional project management experience including technical, financial...Full-timeHybrid workingRemoteFlexible hours
- £43k - £56k per annumEstimated...journals, including minimum 10 years’ experience in a leadership capacity. Experience working in the development sector globally. High-level experience of multilateral development banks’ organizational policies and procedures, including budgeting and human resource...Long-term contract
- £68k - £89k per annumEstimated...intuitive, expressive, and unmistakably Spotify. We’re seeking a Principal Product Manager to help lead the consumer experience across... ...influenced senior leaders and stakeholders across functions and levels to drive alignment and outcomes. You actively use AI tools in your...PrincipalWork from home
- £80k - £105k per annumEstimated...and we hope to be a match for you too. About the Team The Principal Managing Partner is a trusted advisor and executive liaison, dedicated... ...Sponsors at each phase. What You'll Be Doing Nurture C-level Relationships: Foster strong, authentic connections with key C-...PrincipalLong-term contractFull-time
- £37k - £49k per annumEstimated...Principals act as the senior second on searches, and will independently lead some Level 2/3 and CFO-1 searches. They blend search design, calibration, and candidate engagement with growing client credibility, while taking increasing responsibility for mentoring, pitch opportunities...PrincipalFull-time
- £80k - £104k per annumEstimated...looking for exceptional talent to join our fast-growing team. The Principal Product Manager is a senior role within Ocean Infinity’s Product... ...successfully, and exceptional stakeholder influence at all levels. Requirements What you will do! Own and articulate the...PrincipalShift work
- £71k - £93k per annumEstimated# Principal Product Manager - PersonalizationSpotifyOn-siteUnited KingdomProduct & OperationsPosted... ...freshness. • You have experience with AI/ML-powered search features — semantic search,... ...You think strategically at the portfolio level — you can synthesize across many...PrincipalLong-term contractTemporaryWork from home
- £130k - £170k per annumEstimated...and the chance to make a lasting impact. Job Summary As a Principal Architect at JPMorganChase within the Infrastructure Platforms Hosting... ...-on software and systems architecture experience at a senior level, with a track record of delivering large-scale, mission-critical...PrincipalLong-term contract
- £69k - £90k per annumEstimated...orientation with exceptional ability to create structured quantitative and qualitative analyses. ~ Operate at company, portfolio and product level — defining and executing a strategy, shaping a vision and translating it into a roadmap with clear business and customer value-based...Principal
- £34k - £45k per annumEstimated...for As we scale our research ambitions, this role is for a scientist who doesn\'t just execute on known problems but defines new... ...shape the direction of the field. Who you are A staff-level or senior ML researcher with a strong publication record in generative modeling...
- £77k - £100k per annumEstimated...adoption. Thanks to continued growth, we are now looking for a Director or Principal to join our Digital Risks Protect Advisory team in London. As... ...Leadership Coach, mentor and develop consultants at all levels, fostering a high performing, inclusive and collaborative culture...PrincipalFull-timeHybrid workingOn-siteRemoteFlexible hours
- £42k - £55k per annumEstimated...Parkinson’s patient brains. We’ve assembled a world-class team to take on this challenge, with ex-Dyson engineers and Nature-published scientists working hand-in-hand. You can learn more about your potential Mytos teammates here: Team Mytos is backed by Y Combinator, the...PrincipalFull-time
- £100k - £130k per annumEstimated...learn about their operational workflows, painpoints, and opportunity areas. Represent the voice of this segment at the Toast leadership level. Data: Develop and track key metrics and KPIs across the customer journey Define pricing, packaging, and go-to-market strategy...PrincipalHybrid workingOn-site
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Scientist (Comp. Bio/ML) - Director Level. Be the first to apply!
Related searches