Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist (Comp. Bio/ML) - Director Level

£25.5 - £29.4 per hourEstimated
Full-time

We’re looking for a Principal Computational Scientist/Director to help translate our foundation models into impactful, real-world discovery workflows. In this role, you’ll provide scientific leadership across model evaluation and applied use cases, ensuring our work stays grounded in the most relevant challenges in drug development and translational research.

You’ll join as a senior individual contributor with leadership and strategy experience at a point where the the team scales. You will act as a key scientific partner to our research team, mentor and support junior colleagues, and work closely with Product and Business Development to turn cutting-edge biology + ML into deliverables that matter for customers.

Requirements

  • PhD in Computational Biology, Machine Learning, Bioinformatics, or a related field, with a strong focus on Transcriptomics OR Genomics + ML , and 2+ years of industry (non-academic) experience OR MSc in a relevant field and 5+ years of industry experience applying ML to Transcriptomics OR Genomics problems
  • Strong understanding of ML/AI methods for biological data (e.g., transformers, VAEs, diffusion models, classical ML )
  • Hands-on experience with modern ML frameworks such as PyTorch (or equivalent)
  • Leadership experience with small teams to work towards defined roadmaps or projects
  • Excellent communication skills — able to translate complex science into clear, actionable insights for technical and non-technical stakeholders
  • Comfortable in a fast-paced, high-iteration environment , moving quickly from prototype → experiment → insight
  • Strong passion for building at the intersection of biology and machine learning
Vacancy posted a month ago
Similar jobs that could be interesting for youBased on the Principal Scientist (Comp. Bio/ML) - Director Level in London vacancy
  • £77k - £102k per annumEstimated
     ...Viator, and TheFork.   About the role: As a Principal Machine Learning Scientist , you will be the technical anchor for our core...  ...systems within the Trips vertical. Translate high-level business goals into concrete ML architectures and scalable production systems.... 
    Principal
    Long-term contract
    Full-time
    Hybrid working
    Remote
    Flexible hours

    Tripadvisor

    London
    a month ago
  • £74k - £99k per annumEstimated
     ...consumer or platform products, including meaningful work with AI, ML, or technically complex systems. ~ Strong technical depth and experience...  ...: explainability, accountability, over-optimisation, and segment-level effects. Understanding of trustworthy AI principles — safety,... 
    Principal
    Shift work

    Expedia Group

    London
    23 hours ago
  • £54k - £72k per annumEstimated
     ...Principal Ecologist /Associate Director - Ecology London Location: London, Greater London, United Kingdom Capabilities: Environmental Office Setup: Hybrid Job ID: #41068 At Jacobs, we're challenging today to reinvent tomorrow by solving the world's most critical... 
    Principal
    Long-term contract
    Hybrid working
    On-site

    Jacobs

    London
    more than 2 months ago
  •  ...We’re looking for a Principal Product Manager to shape how AI creates real value for our customers and for Spendesk, working across squads...  ...sustained customer and business outcomes. Experience with AI, ML, automation, or data products. You don’t need to be an ML engineer... 
    Principal
    On-site
    Remote
    Flexible hours

    Spendesk

    London
    24 days ago
  • £70k - £90k per annumEstimated
      Wealth & Asset Management Discretionary / Advisory Specialist Location: London (Hybrid) | Practice Area: Wealth & Asset Management | Type: Permanent Shape the future of Wealth & Asset Management The Role Capco is a key consulting partner to leading ...
    Principal
    Permanent
    Hybrid working

    Capco

    London
    9 days ago
  • £123k - £129k per annum

     ...impact on the performance of the Waymo Driver. You have: ~ PhD in ML or related in AI/CS, or MSc with a strong academic publication...  ...location, experience, relevant training and education, and skill level.  Waymo employees are also eligible to participate in Waymo’s discretionary... 
    Full-time
    Hybrid working

    Waymo

    London
    a month ago
  • £50k - £66k per annumEstimated
     ...passionate about bettering business and the world through AI. Ready to level up your career at the company leading workforce transformation in...  ...?  Fin's Machine Learning team is responsible for defining new ML features, researching appropriate algorithms and technologies, and... 
    Hybrid working
    On-site
    Work from home

    Fin

    London
    18 days ago
  • £53k - £72k per annumEstimated
     ...TheFork. As our new Senior Machine Learning Scientist you’ll be joining the Tripadvisor...  ...: Act as the technical lead for specific ML projects within your pod. Design and implement...  ...feature distribution shifts). Lead team-level post-mortems and resolve blocking... 
    Hybrid working
    Remote
    Flexible hours
    Shift work

    Tripadvisor

    London
    a month ago
  • £89k - £119k per annumEstimated
     ...A leading organisation is seeking an exceptional Principal/Director–level Management Consultant to play a pivotal role in supporting submissions for the forthcoming Government Commercial Agency(GCA) Consultancy and Professional Services Framework. This specialist consulting... 
    Principal
    Hybrid working
    Flexible hours
    London
    16 days ago
  • £36k - £48k per annumEstimated
     ...from you! We’re looking to appoint a  Principal Hydrologist to join our  Water Civil Engineering...  ...the wider team and Associates/Associate Directors. You'll take ownership and lead on...  ...supporting your ambitions and interests at every level. We will provide you with an inspiring... 
    Principal
    Hybrid working

    Pick Everard

    London
    more than 2 months ago
  • £85k - £115k per annum

     ...execution. Due to continued growth, they are looking to hire a Principal Consultant to focus on the Technology, Media or...  ...~Leading and delivering senior interim mandates (C-suite, Director, Head of level) ~Partnering closely with clients on complex, business-critical... 
    Principal
    Long-term contract
    Permanent
    Interim

    Permanent People

    London
    more than 2 months ago
  • £66.27k - £73.5k per annum

    Principal Clinical Scientist Synnovis Pay Band 8a Main area: Reference Chemistry Grade: Synnovis Pay Band 8a Contract: 15 months (Fixed...  ...to the Consultant Clinical Scientist you will have a high level of responsibility, including being a source of expert advice... 
    Principal
    Permanent
    Full-time
    Fixed-term contract
    Bank staff
    Flexible hours

    Synnovis

    London
    9 days ago
  • £100k - £120k per annum

     ...Are you a BSR Principal Designer ready to lead and build a service line? Do you have the...  ...commercial appetite and drive to step into a Director role? Want to take ownership, shape the...  ...at Director and senior stakeholder level Confident winning work and developing... 
    Principal
    Long-term contract
    Permanent
    Remote
    London
    24 days ago
  • £69k - £90k per annumEstimated
     ...playlists, and more. We’re looking for a Principal Product Manager to lead the Search Personalization...  ...freshness. - You have experience with AI/ML-powered search features — semantic search,...  ...You think strategically at the portfolio level — you can synthesize across many... 
    Principal
    Long-term contract
    Temporary
    Work from home

    Spotify

    London
    19 days ago
  • £50k - £75k per annum

     ...part of continued growth, they're looking to hire experienced search and recruitment professionals at Consultant, Principal Consultant and Associate Partner level. Salary: £50000 - 75000 Location: London Country: United Kingdom Closing Date:... 
    Principal
    Long-term contract
    Permanent

    Permanent People

    London
    more than 2 months ago
  • £65k - £85k per annumEstimated
     ...Vice Principal – Quality of Education | Orion Ravensbourne School Are you an Assistant Principal ready to make the leap into your first...  ...a driven senior leadership team to take the school to its next level. You will set the standard, challenge underperformance, champion... 
    Principal
    Permanent
    Full-time
    On-site

    Orion Ravensbourne School

    Bromley, Greater London
    5 days ago
  • £93k - £148k per annum

     ...articulate hypotheses and solutions, measure them and has used the tools to be able to do this without an analyst Showcases system-level thinking, a proven ability to look beyond the scope of a single product to design interconnected systems Nice-to-haves Finance... 
    Principal
    Full-time

    Wise

    London
    13 days ago
  • £37k - £49k per annumEstimated
     ...Principals act as the senior second on searches, and will independently lead some Level 2/3 and CFO-1 searches. They blend search design, calibration, and candidate engagement with growing client credibility, while taking increasing responsibility for mentoring, pitch opportunities... 
    Principal
    Full-time

    Altima

    London
    a month ago
  • £56k - £73k per annumEstimated
     ...Assessment and Biodiversity Net Gain assessments. Ideally strong botanical skills, including Field Identification Skills Certificate (FISC) level 3+, or demonstrable botanical ability matching this level. Exceptional project management experience including technical, financial... 
    Full-time
    Hybrid working
    Remote
    Flexible hours

    AtkinsRéalis

    London
    5 days ago
  • £69k - £90k per annumEstimated
     ...orientation with exceptional ability to create structured quantitative and qualitative analyses. ~ Operate at company, portfolio and product level — defining and executing a strategy, shaping a vision and translating it into a roadmap with clear business and customer value-based... 
    Principal

    Thoughtworks

    London
    a month ago
  • £77k - £100k per annumEstimated
     ...adoption. Thanks to continued growth, we are now looking for a Director or Principal to join our Digital Risks Protect Advisory team in London. As...  ...Leadership Coach, mentor and develop consultants at all levels, fostering a high performing, inclusive and collaborative culture... 
    Principal
    Full-time
    Hybrid working
    On-site
    Remote
    Flexible hours

    Control Risks

    London
    10 days ago
  • £73k - £93k per annumEstimated
     ...Senior Principal Planner / Planning Manager Location London Contract Type Annually Renewable, Residential, Inside IR35 Start Date ASAP Role Objective Provide senior-level planning and scheduling leadership across complex subsea and offshore EPCIC projects... 
    Principal
    Full-time
    On-site
    Immediate start

    Kintec Recruitment Limited

    London
    a month ago
  • £82k - £112k per annumEstimated
     ...Job Description Management Consulting Principal Director - Insurance Location: Bath, Bristol, London, Hybrid Mobility: Up to 100% Career Level: Principal Director Accenture is a leading global professional services company, providing a broad range of services... 
    Principal
    Long-term contract
    Hybrid working
    On-site

    Accenture

    London
    a month ago
  • £110k per annum

     ...Vice Principal - Curriculum & Quality Waltham Forest College £110,000 + Excellent Pension & Healthcare Benefits Lead Transformation...  ...skills needs and workforce demands. Influence at the Highest Level Work closely with the Chief Executive & Principal, governors... 
    Principal
    Permanent
    Full-time

    Waltham Forest College

    Waltham Forest, Greater London
    16 days ago
  • £35.6k per annum

     ...Position: Assistant Principal with a Specialism in English Contract Type: Full-time Permanent Work Start Date: 04/01/2027 Location: Watford...  ...Head Teacher. Combining strategic leadership with GCSE and A-Level teaching, you will develop curriculum and assessment, strengthen... 
    Principal
    Permanent
    Full-time
    Temporary
    Traineeship
    Term-time
    Monday to Friday

    Hertfordshire

    London
    3 days ago
  • £52k - £66k per annumEstimated
     ...comfortable communicating with and driving decisions at senior levels within the MOD and its supply chain. You will be joining a...  ...your career and professional development. As an Associate Director / Principal Consultant within the AMCL UK&I team, you will be... 
    Principal
    Long-term contract
    Full-time
    No agency
    Flexible hours

    AMCL

    London
    25 days ago
  • £93k - £123k per annumEstimated
     ...and we hope to be a match for you too. About the Team The Principal Managing Partner is a trusted advisor and executive liaison, dedicated...  ...Sponsors at each phase. What You'll Be Doing Nurture C-level Relationships: Foster strong, authentic connections with key C-... 
    Principal
    Long-term contract
    Full-time
    On-site
    Remote
    Flexible hours

    Workday

    London
    18 days ago
  • £84k - £108k per annumEstimated
     ...Trade & Transaction Reporting Director (Managing Principal) Location: London |  Practice Area: Finance, Risk, Regulatory & Financial Crime | Type...  ...The Role Capco is seeking a Managing Principal (Director level) to lead our Trade & Transaction Reporting capability within... 
    Principal
    Permanent

    Capco

    London
    24 days ago
  • £66k - £87k per annumEstimated
     ...and influencing decisions from engineering through to leadership level. Strong software engineering fundamentals, with experience designing...  ...of, or a strong interest in, applying these skills to AI/ML engineering. A strong understanding of how to balance technical... 
    Principal
    Full-time

    ComparetheMarket

    London
    5 days ago
  • £42k - £55k per annumEstimated
     ...Parkinson’s patient brains. We’ve assembled a world-class team to take on this challenge, with ex-Dyson engineers and Nature-published scientists working hand-in-hand. You can learn more about your potential Mytos teammates here:  Team Mytos is backed by Y Combinator, the... 
    Principal
    Full-time

    mytos

    London
    a month ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist (Comp. Bio/ML) - Director Level. Be the first to apply!