Senior Director, Commercial Business Operations & Systems

Build our future together:

We are seeking a strategic and highly experienced leader to serve as Senior Director, Commercial Business Operations and Systems, reporting to the Executive Director, Field Enablement and Engagement Strategy. This individual will lead the Commercial Business Operations and Systems organization — including a US-based Director and an International Director— and will own the strategy, architecture, and end-to-end lifecycle of the organization's customer facing colleague platforms, systems, and processes.

The Senior Director is the organization's deepest functional expert on the systems, processes, and market-level requirements — both US and international — that shape how commercial technology and operational infrastructure come together to power field and customer engagement globally. This remit is a critical, direct feed into how strategy and roadmap decisions are made across the enterprise.

The ideal candidate is a systems thinker with deep commercial technology and process expertise across markets and a track record of driving enterprise-wide transformation — someone who can shape strategy at the enterprise level while leading a team that translates it into rigorous architecture, governance, and global execution for the business and our customer facing colleagues.

When & where:

• Location: In the Sleepy Hollow, NY Office 4 days a week

Discover your role:

Commercial Platform & Systems Strategy

• Own the global strategy, architecture, and roadmap for the commercial organization's full customer facing colleague platforms — ensuring they are designed as an integrated, future-ready whole rather than a collection of point solutions.
• Serve as the organization's deepest functional expert on commercial facing colleague platforms and systems — including the distinct requirements of US and international markets — and ensure that expertise directly shapes strategy and investment decisions, not just their execution.
• Serve as the accountable leader for the health, evolution, and technical direction of these platforms and systems, making build-vs-buy, sequencing, and investment decisions that align to enterprise priorities.
• Own the long-term, 3-5 year platform and systems roadmap, bringing market-level insight (US and international) on emerging technology, regulatory nuance, and competitive dynamics that informs where the roadmap should go.
• Set standards and governance for platform architecture, data flows, and system interoperability across the commercial technology landscape.
• Manage and optimize the commercial technology investment portfolio, ensuring prioritization is transparent, sequenced, and grounded in market-level cases.

Process Strategy & Enterprise Design

• Lead the strategic design and continuous reinvention of the core commercial processes that govern how field and customer-facing teams engage, plan, and implement — including planning, engagement, and performance-management workflows — bringing deep knowledge of requirements to ensure these processes work in practice, not just on paper.
• Establish global and regional process standards and operating models that balance enterprise consistency with the flexibility Business Units and individual markets need to compete effectively, serving as the primary voice for market-level requirements in how those standards are set.
• Identify structural opportunities to simplify, automate, or reimagine commercial processes, using platforms and AI to remove friction and elevate field and customer experience.
• Own the governance model that ensures platforms, systems, and processes evolve together as a coherent commercial operating model, rather than in silos.

Strategic Leadership & Stakeholder Partnership

• Serve as a chief strategic commercial partner and co-owner on the commercial customer facing colleague technology and process agenda across Business Units, IT, Compliance, and Training.
• Represent the platform and process strategy in senior governance forums, business reviews, and enterprise planning cycles, bringing the market and technical expertise needed to build consensus and secure investment.
• Bring an external and forward-looking perspective — informed by industry trends, competitor capabilities, and emerging technology across both US and international markets — to continually challenge and elevate the organization's commercial platform strategy.
• Build the argument for, and lead the change management around, major shifts in how the organization's commercial platforms and processes operate, partnering closely with training teams and ensuring end user capabilities and confidence in using these systems to meet customer needs and advance business priorities.

Global Scale & Portfolio Leadership

• Lead the global portfolio of commercial customer facing colleague platform and process initiatives, ensuring strategic coherence, appropriate sequencing, and disciplined execution across regions and Business Units.
• Partner with Enablement and Business Unit customers to ensure global platform and process strategy reflects real market-level needs and is adopted and adapted appropriately, without compromising enterprise scalability.
• Define the metrics and success framework used to evaluate platform and process performance, and hold the organization accountable to measurable business outcomes.

Team Leadership

• Build, lead, and develop the Commercial Business Operations and Systems team — including a direct-reporting US Director and International Director— fostering a culture of critical thinking, accountability, and high performance.
• Ensure the US and International Director roles are structured so that market-specific requirements (regulatory, cultural, operational) are surfaced early and consistently into the broader strategy and roadmap, rather than treated as after-the-fact localization.
• Serve as a key advisor on organizational design, capability-building, and resourcing needed to deliver the commercial platform and process strategy.

This role requires:

• Bachelor's degree required; MBA or advanced degree preferred.
• 15+ years of progressive experience in commercial technology, business operations, or commercial strategy, ideally within pharmaceutical, biotech, or another regulated industry.
• Demonstrated experience owning the strategy and architecture of commercial platforms and systems (CRM, digital engagement platforms) at an enterprise or global scale, including direct experience with both US and international market requirements.
• Strong understanding of the market rules, regulations, and compliance requirements that govern commercial engagement across geographies (e.g., promotional regulations, data privacy standards, and HCP/customer engagement codes), and the ability to design platforms and processes that meet these requirements by design.
• Proven ability to design a global vision and strategy while architecting harmonized, market- and region-specific programs — balancing enterprise-wide consistency with the flexibility individual regions or markets need to operate effectively and compliantly.
• Strong track record of leading large-scale process transformation and operating-model design across a matrixed, multi-business-unit organization.
• Systems-level thinking, with the ability to see across platforms, processes, and organizational boundaries to design a coherent commercial operating model.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)