Principal Scientist (In Vitro DMPK)

Job Introduction

Position: Principal Scientist (In Vitro DMPK)

Location: Hoddesdon

About Pharmaron

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.

We're proud of the impact we make and just last year, we supported

887 discovery projects , 1,100+ CMC programs , and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers . To learn more, visit

About The Role

We are looking for a Principal Scientist to join our In Vitro DMPK Assay group at our Hoddesdon site supporting Discovery ADME screening through to early development (e.g. studies associated with ICHM12).

In this role you will work closely with clients, internal stakeholders and the team to deliver a range of bespoke and/or scalable DMPK Assays.You will apply laboratory robotics, automation and efficient data curation processes to support a wide diversity of in vitro endpoints (including intrinsic clearance, cell permeability, drug transporter, binding measurements).

You will contribute to the UK Discovery strategy looking to drive growth and attract new business via excellent delivery of current in vitro DMPK platforms, novel assays and innovative ways of working.

Key Responsibilities

• Take a leading role for the UK in vitro assay platform with strong scientific expertise, and up-to-date knowledge of cutting-edge techniques
• Support partner projects across a diverse portfolio of drug target classes and therapeutic areas.
• Contribute to maintaining a high performing, passionate team responsive to client needs through strong oversight of group objectives, plus coaching and mentoring junior team members.
• Ensure continued project and contract delivery to our partners and to enhance the scientific reputation of Pharmaron with its scientific and commercial stakeholders.
• Collaborate with the Business Development group in building the in vitro DMPK client base.
• Critically develop plans and proposals for new projects, working with partners to implement them successfully.
• Critically analyse, interpret results and integrate data sets to drive projects forward and generate timely key decision making data.
• Apply innovative problem solving to complex, multicellular in vitro models and across drug discovery projects leading to client satisfaction.
• Lead process improvement/new service development projects
• Provide expert scientific leadership and technical expertise across a range of DMPK assays and screens.
• Assist in the development of Pharmaron DMPK reputation though external groups, networks and publications.

Candidate Profile

• An MSc or a BSc in Biochemistry, Chemistry or related subjects with significant industrial experience working in the DMPK field
• Demonstrable track record of applying in vitro ADME knowledge, delivering for projects and solving problems
• Highly commercially orientated, able to demonstrate how delivery excellence can create competitive advantage to deliver and sustain business growth.
• Experience managing technical teams, setting objectives successfully developing self and staff
• Strong leadership abilities with a ‘lead by example’ example approach that is embraced, respected and valued by team members
• Effective written and oral communication skills, including the ability to effectively present scientific findings to colleagues and good scientific judgement.
• Excellent interpersonal skills with the ability to build strong working relationships with stakeholders and customers

Why Pharmaron?

Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

How to Apply

Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.

As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.