Staff Software Engineer (Python & AI Systems) | EU
- Remote job
About the Hiring Process
When you apply, our AI-powered matching platform considers you not only for this opportunity, but also for other relevant roles across our network, so one application can unlock multiple career opportunities.
We only work with real companies hiring for live positions. Every opportunity on our platform is an active search. If there's a strong match, we'll guide you through the process. If not, we won't ignore you.
About the Company
Our client is an ambitious healthcare AI startup building autonomous AI clinicians capable of transforming the future of healthcare.
Their mission is to automate clinical workflows through advanced AI agents, enabling healthcare providers to deliver faster, more accessible, and higher-quality patient care at scale.
Working at the intersection of AI, distributed systems, and healthcare, they're building production-grade infrastructure designed to power the next generation of intelligent healthcare.
- Location: Europe (Remote)
- Employment Type: Full-time (Permanent or B2B)
- Level: Senior Level (Staff Engineer)
- Work Authorization: Must have existing work authorization in an EU country. Employment is available across Europe through an Employer of Record (EOR) where applicable.
About the Role
We're looking for a Staff Software Engineer to design, build, and scale the distributed systems powering autonomous AI clinicians.
This is a highly hands-on, Python-first engineering role focused on production systems, AI infrastructure, and large-scale backend architecture. You'll help shape technical direction while remaining deeply involved in implementation, partnering closely with founders and engineering teammates to solve complex, real-world healthcare challenges.
What You'll Do
AI Platform Engineering;
- Design and scale AI agents for healthcare applications
- Build distributed backend systems supporting AI-driven clinical workflows
- Develop secure healthcare infrastructure for enterprise customers
- Work on LLM, reinforcement learning, and agent-based architectures
System Architecture;
- Design scalable production architectures
- Improve reliability, scalability, and system performance
- Own critical engineering decisions across distributed systems
- Continuously optimize infrastructure and application performance
Technical Leadership;
- Support engineers through code reviews and technical mentorship
- Drive engineering best practices and architecture discussions
- Collaborate closely with founders and product teams
- Help maintain a high engineering bar across the organization
Product Development;
- Translate ambiguous product requirements into production systems
- Ship features rapidly while maintaining engineering quality
- Collaborate across engineering, product, and customer teams
What We're Looking For
Must Have;
- 7+ years building production software systems
- Strong Python engineering experience
- Experience designing distributed systems at scale
- Excellent system design and architecture skills
- Proven experience turning ambiguity into scalable solutions
- Strong backend engineering fundamentals
- Startup or high-growth company experience
- Experience mentoring engineers through technical leadership
- High ownership and builder mindset
- Excellent communication skills
- Based in Europe
Nice to Have;
- Healthcare technology experience
- AI, LLM, or Agentic AI experience
- Reinforcement Learning
- Cloud infrastructure (AWS, GCP, Azure)
- Enterprise software experience
- Open-source contributions
- Experience building products from zero to production
- Background in Computer Science, Mathematics, or Physics
What We Offer
- Competitive salary
- Meaningful equity package
- Fully remote across Europe
- Flexible employment (Permanent or B2B)
- High ownership from day one
- Direct collaboration with founders
- Small, elite engineering team
- Opportunity to shape core technical architecture
- Mission-driven work solving one of healthcare's biggest challenges
If you're passionate about building production AI systems that can transform healthcare and want to help shape the future of autonomous clinical intelligence, we'd love to hear from you...
€100k - €200k per annum
...Hiring Process When you apply, our AI-powered matching platform considers you not... ...Their mission is ambitious: create AI systems that can automate clinical workflows, assist... ...Role We're looking for a Principal Software Engineer to design and build the core infrastructure...SuggestedRemote jobPermanentFull-timeFlexible hours- £62k - £81k per annumEstimated...you on the team. Visit to learn more. As a Senior Software Engineer on the Cards Experience EU team, you'll be a key technical contributor in building... ...across multiple European hubs, collaborating closely with staff engineers and cross-functional partners to deliver...SuggestedLong-term contractHybrid workingRelocation packageOn-siteImmediate start3 days/week
- £73k - £97k per annumEstimated...governments and developers, we are improving the global financial system and creating greater economic fairness and opportunity for... ..., join us, and build real world value. THE WORK: As a Staff Software Engineer on Ripple's Authentication and Authorization platform team,...SuggestedFull-timeHybrid workingOn-site
- £96k - £128k per annumEstimated...developers, we are improving the global financial system and creating greater economic fairness... ...real world value. The Work As a Staff Engineer, Frontend, you will be working on... ...leverage the right tools for the job—including AI assistants —to be efficient, but you are...SuggestedFull-timeOn-site
€85k - €160k per annum
...Hiring Process When you apply, our AI-powered matching platform considers you not... ...they're building one of the defining AI software categories of the coming decade. Location... ...We're looking for an exceptional AI Systems Engineer who thrives on ownership, speed, and...SuggestedFull-timeVisa supportRelocation packageVisa sponsorshipRelocationAfternoon shift£130k - £150k per annum
...contributor in designing and developing bleeding edge software and compilers, you will play a pivotal role... ...of the next generation of computing systems. Stack leans heavily on Python and C++, machine learning, INSERT YOUR OWN AI BUZZWORD HERE, think Pytorch, Compilers,...Permanent5 days/week£130k - £170k per annum
...AI, Compilers, HPC, Low-latency systems, Python/C++, if any of those get you excited, then keep reading... Let’s talk about the next trillion-dollar problem... ...real time collaboration with some of the smartest engineers in the industry. I know, I know... remote work is the...PermanentRelocation packageOn-siteRemote£325k - £390k per annum
...create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for... ...growing group of committed researchers, engineers, policy experts, and business leaders... ...environment Have strong proficiency in Python, Rust and/or Go Are obsessed with...Long-term contractHybrid workingVisa sponsorshipOn-siteRemoteFlexible hours- £42k - £55k per annumEstimated...Software Engineer (AI System) Development, deploy and maintain AI systems and services in the healthcare domain to find more untreated patients About Pangaea Data Pangaea Data (Pangaea) is a South San Francisco and London based business founded by Dr Vibhor Gupta and...Full-timeFlexible hours
- £80k - £104k per annumEstimated...Visit to learn more. Are you a Software Engineer who thrives on real ownership? At Perk,... ...by the reliability and simplicity of the systems you build to power a global platform.... ...we trust our people to deliver it. AI at Perk AI is embedded in how we work...Long-term contractHybrid workingRelocation packageOn-site3 days/week
- ...left operators tied to legacy systems, making critical decisions on... ...energy that lets companies use AI at scale, harnessing all of their... ...As a Senior Full Stack Engineer on the Core AI team, you will... ...with AI research, Infra, and software teams to translate complex industrial...Long-term contractOn-siteRemote
- ...to make mobility ecological, efficient and convenient. The Role As a Staff Software Engineer, you will be a technical leader in our Data Science Products team and in the Data, Analytics and AI organisation of Arrive. The Data Science Products team ingests billions of...Hybrid workingOn-siteWork from homeFlexible hours
- £98k - £129k per annumEstimated...partners through world-class software, purpose-built for everyone in... ...Work With You’ll enter our engineering interview process as part of a... ...specific team’s immediate gap. Staff Engineers at Carta are... ...heart of the platform, shaping a system that unifies front-office intelligence...Long-term contractOn-siteImmediate start
- £88k - £116k per annumEstimated...Graphcore, we’re building the future of AI compute. We’re a team of semiconductor, software and AI experts, with deep... ...maintaining high-quality software systems. The role focuses on testing and... ...software architecture, automation, and engineering best practices. The ideal...Long-term contractVisa supportOn-siteFlexible hours
- £59k - £77k per annumEstimated...White Collar Factory (95009), United Kingdom, London, London Staff Software Engineer - Machine Learning About this role We’re on a mission to transform the way we use data and AI to service our customers and drive efficiency across the business. Do you love...PermanentHybrid workingOn-siteImmediate startFlexible hours
- ...Benefits We are looking for an experienced Staff Engineer with an excellent track record of... ...identify and leverage the latest Generative AI tools and techniques to drive innovation... ...on it. You translate this into a target system and data architecture with clear milestones...Full-timeHybrid workingOn-siteFlexible hours
£325k per annum
...reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for... ...growing group of committed researchers, engineers, policy experts, and business leaders working... ...Minimum qualifications Significant software engineering experience building and...Long-term contractHybrid workingVisa sponsorshipOn-siteFlexible hours- £67k - £89k per annumEstimated...Join us to shape the future of AI-driven business operations. You... ...expertise in building multi-agent systems and your passion for... ...continuous improvement. As an AI Engineer in our Agentic AI Solutions team... ...scikit-learn. Proficiency in Python; experience writing comprehensive...Long-term contract
- £64k - £84k per annumEstimated...platform and curriculum, developed in partnership with Nebius AI. Our team is fully remote and globally distributed, and we... ...both regions. We're building a program for experienced engineers transitioning into system architecture roles. We need AI Systems Engineering...On-siteRemoteFlexible hours
- £80k - £104k per annumEstimatedStaff Software Engineer – Code Foundations Job ID: R20799 Technology London - The River Building HQ Ready to apply? Get started with... ...a global, three-sided marketplace, building and scaling systems that serve millions of customers, riders and partners every...Hourly payLong-term contractFull-timeSummer workRelocation packageOn-siteWork from homeFlexible hours1 day/week
- £70k - £93k per annumEstimated...industry, Anduril is changing how military systems are designed, built and sold. Anduril’s... ...of systems is powered by Lattice OS, an AI-powered operating system that turns thousands... ...JOB We're looking for a highly driven software engineer to help make our simulation capabilities...Full-timeImmediate start
£325k - £395k per annum
...Back to jobs Staff+ Software Engineer, Safeguards Infrastructure London, UK About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team...Long-term contractFull-timeHybrid workingVisa sponsorshipOn-siteFlexible hours- £78k - £103k per annumEstimated...Global Public Sector team is focused on using AI to address critical challenges facing the... ...the impact of AI As a Full Stack Software Engineer (Forward Deployed), you’ll collaborate directly... ...for how interactive UIs, backend systems, and AI models are integrated at scale to...Long-term contractShift work
- £105k - £135k per annumEstimated...About Engineering at Fonoa Engineering is central to how we build the... ...with modern technologies (LLMs, AI Agents, etc.) to solve meaningful... ...– scalable, maintainable systems are non-negotiable Speed &... ...Position Overview As a Staff Engineer , your role is to improve...Long-term contractFull-time
£10 per hour
...The Role The Software team at CoMind spans the full stack of a regulated... ...— from embedded and real-time systems through application software,... ..., GUI, DevOps, and test engineering. It is a team that builds across... ...environments. As a Staff Software Engineer , you will...Long-term contractFull-timeOn-siteRemoteWork from homeFlexible hours- £146k - £187k per annumEstimated...massive datasets in real time to building systems that operate reliably on a global scale.... ...to meet you. What we do Our Software Engineers are end-to-end owners who have the opportunity... ...user interfaces – to name a few. Staff Engineers contribute to more than our product...
- ...About Engineering at Fonoa Engineering is central to how we build the... ...with modern technologies (LLMs, AI Agents, etc.) to solve meaningful... ...– scalable, maintainable systems are non-negotiable Speed &... ...are looking for a Senior or Staff Software Engineer to help us...Long-term contractFull-time
£325k per annum
...create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for... ...growing group of committed researchers, engineers, policy experts, and business leaders... ...one systems language (e.g., Rust, Go, or Python), IaC proficiency with Terraform. Hands...Long-term contractHybrid workingVisa sponsorshipOn-siteFlexible hours£325k - £390k per annum
...Back to jobs Staff Software Engineer, AI Reliability Engineering London, UK About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team...Long-term contractFull-timeHybrid workingVisa sponsorshipOn-siteFlexible hours- £116k - £148k per annumEstimated...In June 2025, Tessl was ranked #2 in Sifted EU’s 2025 B2B SaaS Rising 100. At Tessl, we believe AI will truly transform software development. AI Native Developers will... ...landscape. Overview of role Join our engineering team to build real-time AI Native workflows...Long-term contractFull-timeOn-siteMonday to Thursday3 days/week
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Staff Software Engineer (Python & AI Systems) | EU. Be the first to apply!
- senior staff software engineer London
- staff software engineer London
- python developer financial trading London
- front office fixed income c++python developer London
- graduate junior developer python javascript php London
- junior python engineer London
- junior python developer London
- part time python developer London
- python developer London
- developer oracle python London
