Clinical Bioinformatician

Job summary
We are seeking a skilled and enthusiastic Clinical Bioinformatician to join our team based in the North Thames Genomic Laboratory Hub at Great Ormond Street Hospital. Our team is delivering transformation in patient care by developing pipelines for rapid, comprehensive diagnosis of rare diseases.

If you are committed to contributing to a team delivering excellence in rare disease bioinformatics this is definitely the post for you.

You will be joining an enthusiastic, friendly, motivated Clinical Bioinformatics Team. This is an ideal opportunity to seriously contribute to clinical practice for the benefit of patients. This post is suitable for registered Clinical Bioinformaticians or Trainee Bioinformaticians close to registration.

The role includes a minimum requirement of 20% onsite working, although the expectation is that you will work onsite for 40% of the week to support service delivery, collaboration and team integration.

Main duties of the job
You will be working within a team of Bioinformaticians supporting diagnostics services at Great Ormond Street Hospital. The role will be a mix of acting as Duty Bioinformatician, development work and data analysis to support the rare disease diagnostic service. The Duty Bioinformatician ensures the smooth operational delivery of the service and answers daily issues raised by the scientific teams. Development work includes working on new and updating existing pipelines and database projects, as well as evaluations of applications and infrastructure planning. Supporting scientific and clinical teams is also an important part of the role, requiring strong data analysis and presentation skills.

It is likely that the majority of the role will be supporting the development of the service, but individuals will need to cover all aspects of the role. Having a broad set of programming skills and IT knowledge will be required. You will be responsible for ensuring that all work is completed to a high standard within defined timelines. You will be expected to work efficiently as part of the Bioinformatics Team and as a supportive team member.Compliance with UKAS ISO15189 standards is required, along with ensuring that the bioinformatics quality standards are maintained.

About us
We are keen to make our workforce as diverse asthe communities we serve, and we hope to attract applications from underrepresented groups, includingpeople withBlack, Asian and Minority Ethnicheritage, people with a disability, and peoplefrom LGBTQ+ communities.By growing an ever more diverse workforce, we'll have a greater range of perspectives and knowledge, meaning that we can provide the children andyoung people at our hospital with even better care.

Our hospital is committed to creating an environmentthat is open and inclusive. Our staff are encouragedto engage with colleagues through the following networks: REACH (Race, Ethnicity and Cultural Heritage) ENABLED (Enhancing Abilities & Leveraging Disabilities Network), PRIDEandWomen's networks; all of which are sponsored by a member of our Executive Management Team.

We want to ensure that all of our people, regardless of their background, are seen and heard. We want to attract applicants that share our commitment to inclusion and that understand diversity is a strength that is embraced and valued.

formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.

Details
Date posted: 09 September 2026
Pay scheme: Agenda for change
Band: Band 7
Salary: £58,133 to £65,261 a year
Inclusive per annum
Contract: Permanent
Working pattern: Full-time
Reference number: 271-GEN-8204714
Job locations:
Great Ormond Street Hospital for Children NHS Foundation Trust
Great Ormond Street Hospital
London
WC1N 3JH
United Kingdom

Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience, and knowledge required. For both documents please view the attachment.

Person Specification
GOSH Culture and Values
Essential

• Our Always values
• Able to work on site when required

Academic/Professional qualification/Training
Essential

• State Registered Clinical Bioinformatician (HCPC)
• MSc in Bioinformatics/Computational Biology or equivalent Postgraduate qualification

Desirable

• Higher degree (PhD) in Bioinformatics or a related field

Experience/Knowledge
Essential

• Advanced knowledge of the Python programming language, and commonly used Python libraries and web frameworks (e.g. Django and Flask)
• Knowledge of confidentiality and data protection processes and procedures
• Experience of developing, implementing and maintaining bioinformatic data analysis pipelines
• Experience with creating, querying and maintaining databases, particularly MySQL or PostgreSQL
• Advanced use of git version control
• Demonstrable experience in a clinical diagnostic department
• Knowledge of bash and shell scripting
• Ability to work in a Unix/Linux environment
• Up to date knowledge of the relevant scientific literature
• Evidence of professional and personal development.
• Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow)

Desirable

• Experience using docker for development
• Experience deploying software in the cloud

Skills/Abilities
Essential

• Excellent organisational and time management skills with ability to prioritise tasks effectively
• Ability to develop and maintain excellent communication and working relationships
• Able to provide specialist advice to laboratory staff
• Able to present data at departmental and inter-departmental meetings
• Awareness of clinical significance of genetics findings and implications for patients
• Work to deadlines, operating autonomously and as part of a team
• Knowledge and understanding of ISO15189 accreditation standards and their application to a genomics laboratory
• Ability to write and follow bioinformatics protocols

Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration
Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details
Employer name: Great Ormond Street Hospital for Children NHS Foundation Trust
Address: Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street Hospital, London, WC1N 3JH, United Kingdom
Employer's website:

Employer contact details
For questions about the job, contact:
Principle Bioinformatician
Patrick Lombard
View email address on meeveem.com

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).