Principal Software Engineer (Python & AI Systems) | EU

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About the Company

Our client is an early-stage healthcare AI startup building autonomous AI clinicians capable of transforming how healthcare is delivered.

Their mission is ambitious: create AI systems that can automate clinical workflows, assist healthcare professionals, and ultimately make high-quality healthcare accessible to everyone.

Working at the intersection of AI, distributed systems, and healthcare, they're building production-grade technology designed to solve one of humanity's most important challenges.

• Location: Europe (Remote)
• Employment Type: Full-time (Permanent or B2B)
• Level: Principal Individual Contributor
• Work Authorization: Must be based within the European Union (hired via Deel where applicable)

About the Role

We're looking for a Principal Software Engineer to design and build the core infrastructure powering autonomous AI clinicians.

This is a highly hands-on engineering role focused on building large-scale distributed systems, AI agents, secure healthcare infrastructure, and production-grade backend platforms. You'll work directly with founders, hospitals, and healthcare providers to solve complex technical problems that have real-world impact.

If you're a builder who thrives in ambiguity, enjoys solving difficult engineering challenges, and wants to shape the future of AI-powered healthcare, we'd love to hear from you.

What You'll Do

AI Platform Engineering;

• Architect and build AI agent systems for healthcare applications
• Design scalable distributed backend services
• Develop secure healthcare infrastructure handling sensitive clinical data
• Build low-latency communication systems supporting voice and video workflows

Production Engineering;

• Build scalable Python services powering enterprise healthcare platforms
• Design APIs, orchestration systems, and backend infrastructure
• Optimize system performance, scalability, and reliability
• Improve deployment, monitoring, and operational excellence

AI Systems;

• Build production systems around LLMs, AI agents, and reinforcement learning
• Design agent orchestration frameworks
• Integrate AI capabilities into real-world healthcare workflows
• Continuously improve system accuracy and operational performance

Technical Leadership;

• Translate ambiguous product challenges into scalable engineering solutions
• Partner directly with founders and product teams
• Help shape technical architecture and engineering standards
• Mentor engineers through technical leadership and example

What We're Looking For

Must Have;

• 5+ years building complex production software systems
• Strong Python engineering experience
• Experience designing scalable distributed systems
• Track record of building production-grade backend platforms
• Experience turning ambiguous requirements into reliable solutions
• Strong system design and architecture skills
• Startup or high-growth company experience
• High ownership and strong problem-solving mindset
• Excellent communication skills
• Based in Europe

Nice to Have;

• Healthcare technology experience
• AI, LLM, or Agentic AI experience
• Reinforcement Learning
• Cloud infrastructure (AWS, GCP, Azure)
• Enterprise software experience
• Open-source contributions
• Background in Mathematics, Computer Science, or Physics
• Experience building products from zero to production

What We Offer

• €100,000–€200,000 salary
• Meaningful equity package
• Fully remote across Europe
• Flexible employment (Permanent or B2B)
• Opportunity to work directly with founders
• High ownership from day one
• Small, elite engineering team
• Mission-driven work solving one of healthcare's biggest challenges
• Opportunity to build technology with global impact

If you're excited about building production AI systems that could redefine the future of healthcare, we'd love to hear from you...